Middle Mississippi River National Wildlife Refuge Middle Mississippi River National Wildlife RefugeStation reference point Beaver Island (Special regs)256 acres Crains Island - IL (Special regs)641 acres Crains Island - MO (Special regs)103 acres Harlow Island (Special regs)1,191 acres Horse Island (Special regs)2,049 acres Meissner Island (Special regs)103 acres Rockwood Island (Special regs)1,263 acres Wilkinson Island - IL (Special regs)1,928 acres Wilkinson Island - MO (Special regs)715 acres Closed Unit (Closed)179 acres